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House Fly Death by Artificial Sweetener: Starvation, Not Toxicity

musca domestica

In a study on the effects of artificial sweeteners on house flies (Musca domestica), researchers found that a diet of only erythritol can indeed be fatal to the flies—but the effect appears to be the result of a lack of caloric content, not toxicity. (Photo credit: Pest and Diseases Image Library,

While recent headlines have noted the potential insecticidal properties of common artificial sweeteners, don’t go sprinkling Truvia around your home just yet. A new study on house flies suggests they likely aren’t poisoned by sweeteners—they just die of malnutrition.

A team of researchers at North Carolina State University tested survival rates of house flies (Musca domestica), on erythritol—the main ingredient in Truvia—compared to natural sugar, agar, and water alone. In their study, published today in the Journal of Medical Entomology, they found that the flies both strongly preferred high-calorie natural sugar when presented with the choice and, when fed only erythritol, they died no faster than when fed only water or agar.

“Based on our results, erythritol does not appear to have insecticidal properties on house flies in the traditional sense, and would not be a candidate for adult control,” says Michael Fisher, BCE, lead author on the study and a doctoral candidate at NC State.

Fisher and colleagues also tested mannitol, xylitol, and sorbitol, and found only the sorbitol to have any nutritive value for flies. They identify several possible reasons for the flies’ inability to survive on artificial sweeteners, including an inability to digest them, a negative interaction with flies’ gut microbes, or digestive blockage caused by the sweeteners. But, while the sweeteners led to high mortality in a lab setting, real-world applications would face practical challenges.

“In nature, and your backyard or livestock operation for that matter, there would be a number of competing food sources,” says Fisher. “Ideally, if some type of attractive toxic sugar bait could be developed for house flies or other filth flies, it is important to address attraction, preference, and stimulation of feeding to achieve effective control.”

Journal of Medical EntomologyRead More

Survival of the House Fly (Diptera: Muscidae) on Truvia and Other Sweeteners

Journal of Medical Entomology



  1. That would be a “sweet” way to knock off fly problems everywhere! Big Stinkies and we call them and other fly traps and so forth work but whew!, Black fly season near the Blue Ridge with orchards and chicken farms around…. Somebody GET ON IT!

  2. This method is a short cut. We have plant materials that will render housefly useless. Is mixing the plant materials with the sweeteners then necessary?

    • No…it is not necessary because the Musca Domesticas would still be able to get the nutrition it needs from the plants that you are lacing with sweeteners.

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